Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
应用类型
WB,ICC
免疫原
This CD34 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 320-354 amino acids from the C-terminal region of human CD34.