HSP90 proteins are highly conserved molecular chaperonesnthat have key roles in signal transduction, protein folding,nprotein degradation, and morphologic evolution. HSP90 proteinsnnormally associate with other cochaperones and play important rolesnin folding newly synthesized proteins or stabilizing and refoldingndenatured proteins after stress. HSP90B1 is an endoplasmicnreticulum HSP90 protein. Other HSP90 proteins are found in cytosoln(see HSP90AA1; MIM 140571) and mitochondria (TRAP1; MIM 606219)n(Chen et al., 2005 [PubMed 16269234]).
应用类型
WB,IHC,FCM
免疫原
This HSP90B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 460-487 amino acids from the Central region of human HSP90B1.
