Histones are basic nuclear proteins that are responsiblenfor the nucleosome structure of the chromosomal fiber inneukaryotes. Two molecules of each of the four core histones (H2A,nH2B, H3, and H4) form an octamer, around which approximately 146 bpnof DNA is wrapped in repeating units, called nucleosomes. Thenlinker histone, H1, interacts with linker DNA between nucleosomesnand functions in the compaction of chromatin into higher ordernstructures. This gene is intronless and encodes a member of thenhistone H2B family. Transcripts from this gene lack polyA tails butninstead contain a palindromic termination element. This gene isnfound in the histone microcluster on chromosome 6p21.33. [providednby RefSeq].
应用类型
WB,IHC,FCM
免疫原
This HIST1H2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-86 amino acids from the Central region of human HIST1H2BJ.
