CALCR is a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis.
应用类型
WB,ICC,FCM
免疫原
This CALCR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids of human CALCR.
