Required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex. Facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF- alpha induced NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain.
应用类型
WB
免疫原
This RSF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1355-1389 amino acids from the C-terminal region of human RSF1.