Mutations in this gene lead to tuberous sclerosis complex.nIts gene product is believed to be a tumor suppressor and is ablento stimulate specific GTPases. The protein associates with hamartinnin a cytosolic complex, possibly acting as a chaperone fornhamartin. Alternative splicing results in multiple transcriptnvariants encoding different isoforms.
应用类型
WB
免疫原
This TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1096 of human TSC2.
