Cancer-associated chromosomal changes often involvenregions containing fragile sites. This gene maps to a commomnfragile site on chromosome 7q31.2 designated FRA7G. This gene isnsimilar to mouse Testin, a testosterone-responsive gene encoding anSertoli cell secretory protein containing three LIM domains. LIMndomains are double zinc-finger motifs that mediate protein-proteinninteractions between transcription factors, cytoskeletal proteinsnand signaling proteins. Multiple protein isoforms are encoded byntranscript variants of this gene.
应用类型
WB
免疫原
This TES antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human TES.
