This gene encodes an integral outer mitochondrial membranenprotein that blocks the apoptotic death of some cells such asnlymphocytes. Constitutive expression of BCL2, such as in the casenof translocation of BCL2 to Ig heavy chain locus, is thought to benthe cause of follicular lymphoma. Two transcript variants, producednby alternate splicing, differ in their C-terminal ends. [providednby RefSeq].
应用类型
WB
免疫原
This bcl-2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S70 of human bcl-2.
