NMYC interactor (NMI) encodes a protein that interactsnwith NMYC and CMYC (two members of the oncogene Myc family), andnother transcription factors containing a Zip, HLH, or HLH-Zipnmotif. The NMI protein also interacts with all STATs except STAT2nand augments STAT-mediated transcription in response to cytokinesnIL2 and IFN-gamma. The NMI mRNA has low expression levels in allnhuman fetal and adult tissues tested except brain and has highnexpression in cancer cell line-myeloid leukemias. [provided bynRefSeq].
应用类型
WB
免疫原
This NMI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human NMI.