DNA (cytosine-5-)-methyltransferase 1 has a role in thenestablishment and regulation of tissue-specific patterns ofnmethylated cytosine residues. Aberrant methylation patterns arenassociated with certain human tumors and developmentalnabnormalities. Two transcript variants encoding different isoformsnhave been found for this gene.
应用类型
WB
免疫原
This Dnmt1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1105 of human Dnmt1.
