This gene is a member of the frizzled gene family. Membersnof this family encode seven-transmembrane domain proteins that arenreceptors for the Wingless type MMTV integration site family ofnsignaling proteins. Most frizzled receptors are coupled to thenbeta-catenin canonical signaling pathway. The function of thisnprotein is unknown, although it may play a role in mammalian hairnfollicle development.
应用类型
WB
免疫原
This FZD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-525 amino acids from the C-terminal region of human FZD3.