The protein encoded by this gene belongs to thenG-protein-coupled receptor family . It is a receptor for the CCnchemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a groupnof small polypeptide, structurally related molecules that regulatencell trafficking of various types of leukocytes. The chemokinesnalso play fundamental roles in the development, homeostasis, andnfunction of the immune system, and they have effects on cells ofnthe central nervous system as well as on endothelial cells involvednin angiogenesis or angiostasis.
应用类型
WB
免疫原
This CCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the C-terminal region of human CCR4.
