The protein encoded by this gene is a type-1 membranenglycoprotein, which contains two immunoglobulin domains, and thusnbelongs to the immunoglobulin superfamily. Studies of the relatedngenes in mouse and rat suggest that this gene may regulate myeloidncell activity and delivers an inhibitory signal for the macrophagenlineage in diverse tissues. Multiple alternatively splicedntranscript variants that encode different isoforms have been foundnfor this gene.
应用类型
WB
免疫原
This CD200 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-211 amino acids from the C-terminal region of human CD200.