Small G proteins of the RAB family (see MIM 179508)nfunction in intracellular vesicle trafficking by switching from thenGTP-bound state to the GDP-bound state with the assistance ofnguanine nucleotide exchange factors (GEFs; see MIM 609700) andnGTPase-activating proteins (GAPs). TBC1D10B functions as a GAP fornseveral proteins of the Rab family (Ishibashi et al., 2009 [PubMedn19077034]).
应用类型
WB
免疫原
This TBC1D10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-808 amino acids from the C-terminal region of human TBC1D10B.
