This gene may play a role in regulation of the innatenimmune response. The encoded protein is upregulated in response tonviral infection and may be involved in mediation of tumor necrosisnfactor-alpha proinflammatory responses. Mutations in this gene havenbeen associated with Aicardi-Goutieres syndrome. [provided bynRefSeq].
应用类型
WB
免疫原
This SAMHD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-230 amino acids from the Central region of human SAMHD1.