Members of the F-box protein family, such as FBXW9, arencharacterized by an approximately 40-amino acid F-box motif. SCFncomplexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIMn603034), and F-box proteins, act as protein-ubiquitin ligases.nF-box proteins interact with SKP1 through the F box, and theyninteract with ubiquitination targets through other proteinninteraction domains (Jin et al., 2004 [PubMed 15520277]).[suppliednby OMIM].
应用类型
WB
免疫原
This FBXW9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-31 amino acids from the N-terminal region of human FBXW9.
