SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) formnESCRT-II (endosomal sorting complex required for transport II), ancomplex involved in endocytosis of ubiquitinated membrane proteins.nSNF8, VPS25, and VPS36 are also associated in a multiproteinncomplex with RNA polymerase II elongation factor (ELL; MIM 600284)n(Slagsvold et al., 2005 [PubMed 15755741]; Kamura et al., 2001n[PubMed 11278625]).
应用类型
WB
免疫原
This SNF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human SNF8.
