MARCH9 is a member of the MARCH family of membrane-boundnE3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitinn(see MIM 191339) to target lysines in substrate proteins, therebynsignaling their vesicular transport between membrane compartments.nMARCH9 induces internalization of several membrane glycoproteinsnand directs them to the endosomal compartment (Bartee et al., 2004n[PubMed 14722266]; Hoer et al., 2007 [PubMed 17174307]).[suppliednby OMIM].
应用类型
WB
免疫原
This MARCH9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-330 amino acids from the C-terminal region of human MARCH9.