The modification of proteins with ubiquitin is annimportant cellular mechanism for targeting abnormal or short-livednproteins for degradation. Ubiquitination involves at least threenclasses of enzymes: ubiquitin-activating enzymes, or E1s,nubiquitin-conjugating enzymes, or E2s, and ubiquitin-proteinnligases, or E3s. This gene encodes a member of the E2nubiquitin-conjugating enzyme family and catalyzes the covalentnattachment of ubiquitin to other proteins. The protein may beninvolved in degradation of muscle-specific proteins. [provided bynRefSeq].
应用类型
WB
免疫原
This UBE2G1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-155 amino acids from the C-terminal region of human UBE2G1.