This gene encodes a member of the cytokine type I receptornfamily. The protein forms a secreted complex withncardiotrophin-like cytokine factor 1 and acts on cells expressingnciliary neurotrophic factor receptors. The complex can promotensurvival of neuronal cells. Mutations in this gene result innCrisponi syndrome and cold-induced sweating syndrome. [provided bynRefSeq].
应用类型
WB
免疫原
This CRLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-283 amino acids from the Central region of human CRLF1.
