Phosphatidylinositolpolyphosphates (PtdInsPs) arencentrally involved in many biologic processes, ranging from cellngrowth and organization of the actin cytoskeleton to endo- andnexocytosis. PI4KII phosphorylates PtdIns at the D-4 position, annessential step in the biosynthesis of PtdInsPs (Barylko et al.,n2001 [PubMed 11244087]).
应用类型
WB
免疫原
This PI4K2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of human PI4K2A.