This gene encodes a member of the membrane-spanning 4Angene family. Members of this nascent protein family arencharacterized by common structural features and similar intron/exonnsplice boundaries and display unique expression patterns amongnhematopoietic cells and nonlymphoid tissues. This gene encodes anB-lymphocyte surface molecule which plays a role in the developmentnand differentiation of B-cells into plasma cells. This familynmember is localized to 11q12, among a cluster of family members.nAlternative splicing of this gene results in two transcriptnvariants which encode the same protein.
应用类型
WB,IHC
免疫原
This MS4A1/CD20 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 266-294 amino acids from the C-terminal region of human MS4A1/CD20.