This gene encodes a serine protease expressed exclusivelynin the thymus. It is thought to play a role in the alternativenantigen presenting pathway used by cortical thymic epithelial cellsnduring the positive selection of T cells. The gene is found in thenlarge histone gene cluster on chromosome 6, near the majornhistocompatibility complex (MHC) class I region. A secondntranscript variant has been described, but its full length naturenhas not been determined.
应用类型
WB
免疫原
This PRSS16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human PRSS16.