The protein encoded by this gene is a member of thenETS-domain transcription factor family and the ternary complexnfactor (TCF) subfamily. Proteins in this subfamily regulatentranscription when recruited by serum response factor to bind tonserum response elements. This protein is activated bynsignal-induced phosphorylation; studies in rodents suggest that itnis a transcriptional inhibitor in the absence of Ras, but activatesntranscription when Ras is present.
应用类型
WB
免疫原
This ELK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the N-terminal region of human ELK3.