NEIL2 belongs to a class of DNA glycosylases homologous tonthe bacterial Fpg/Nei family. These glycosylases initiate the firstnstep in base excision repair by cleaving bases damaged by reactivenoxygen species and introducing a DNA strand break via thenassociated lyase reaction (Bandaru et al., 2002 [PubMedn12509226])
应用类型
WB
免疫原
This NEIL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human NEIL2.
