Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.
应用类型
WB,IHC
免疫原
This MOV10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-288 amino acids from the N-terminal region of human MOV10.
