Alpha-2-macroglobulin is a protease inhibitor and cytokinentransporter. It inhibits many proteases, including trypsin,nthrombin and collagenase. A2M is implicated in Alzheimer diseasen(AD) due to its ability to mediate the clearance and degradation ofnA-beta, the major component of beta-amyloid deposits. [provided bynRefSeq].
应用类型
WB
免疫原
This A2M antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1162-1192 amino acids from the C-terminal region of human A2M.