Kallikreins are a subgroup of serine proteases havingndiverse physiological functions. Growing evidence suggests thatnmany kallikreins are implicated in carcinogenesis and some havenpotential as novel cancer and other disease biomarkers. This genenis one of the fifteen kallikrein subfamily members located in ancluster on chromosome 19. Its encoded protein is secreted and maynplay a role in suppression of tumorigenesis in breast and prostatencancers. Alternate splicing of this gene results in multiplentranscript variants encoding the same protein. [provided bynRefSeq].
应用类型
WB
免疫原
This KLK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from the N-terminal region of human KLK10.