This gene encodes a protein that acts as a repressor ofnbeta-interferon gene expression. The protein binds specifically tonthe PRDI (positive regulatory domain I element) of the beta-IFNngene promoter. Transcription of this gene increases upon virusninduction. Two alternatively spliced transcript variants thatnencode different isoforms have been reported.
应用类型
WB
免疫原
This PRDM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the N-terminal region of human PRDM1.