This gene is located in a cluster of imprinted genes onnchromosome 11p15.5, which is considered to be an important tumornsuppressor gene region. Alterations in this region may benassociated with the Beckwith-Wiedemann syndrome, Wilms tumor,nrhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, andnbreast cancer. This gene has been shown to be imprinted, withnpreferential expression from the maternal allele in placenta andnliver.
应用类型
WB,IHC
免疫原
This PHLDA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the C-terminal region of human PHLDA2.
