Autophagy is a process for the bulk degradation ofncytosolic compartments by lysosomes. ATG10 is an E2-like enzymeninvolved in 2 ubiquitin-like modifications essential fornautophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261)nconjugation and modification of a soluble form of MAP-LC3n(MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to anmembrane-bound form (Nemoto et al., 2003 [PubMedn12890687]).
应用类型
WB,IHC
免疫原
This APG10L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-121 amino acids of human APG10L.
