The structure of the MAS1 product indicates that itnbelongs to the class of receptors that are coupled to GTP-bindingnproteins and share a conserved structural motif, which is describednas a '7-transmembrane segment' following the prediction that thesenhydrophobic segments form membrane-spanning alpha-helices. The MAS1nprotein may be a receptor that, when activated, modulates ancritical component in a growth-regulating pathway to bring aboutnoncogenic effects.
应用类型
WB
免疫原
This MAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-314 amino acids from the C-terminal region of human MAS1.