Tight junctions represent one mode of cell-to-cellnadhesion in epithelial or endothelial cell sheets, formingncontinuous seals around cells and serving as a physical barrier tonprevent solutes and water from passing freely through thenparacellular space. The protein encoded by this immunoglobulinnsuperfamily gene member is localized in the tight junctions betweennhigh endothelial cells. It acts as an adhesive ligand forninteracting with a variety of immune cell types and may play a rolenin lymphocyte homing to secondary lymphoid organs. [provided bynRefSeq].
应用类型
WB,IHC
免疫原
This JAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the N-terminal region of human JAM2.
