The protein encoded by this gene is similar in sequence tonthe amino terminus of Drosophila enhancer of split groucho, anprotein involved in neurogenesis during embryonic development. Thenencoded protein, which belongs to the groucho/TLE family ofnproteins, can function as a homooligomer or as a heteroologimernwith other family members to dominantly repress the expression ofnother family member genes. Three transcript variants encodingndifferent isoforms have been found for this gene. [provided bynRefSeq].
应用类型
WB
免疫原
This AES antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the C-terminal region of human AES.