Polyspecific organic cation transporters in the liver,nkidney, intestine, and other organs are critical for elimination ofnmany endogenous small organic cations as well as a wide array ofndrugs and environmental toxins. This gene is one of three similarncation transporter genes located in a cluster on chromosome 6. Thenencoded protein contains twelve putative transmembrane domains andnis a plasma integral membrane protein. Two transcript variantsnencoding two different isoforms have been found for this gene, butnonly the longer variant encodes a functional transporter. [providednby RefSeq].
应用类型
WB,IHC
免疫原
This SLC22A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511-539 amino acids from the C-terminal region of human SLC22A1.
