Nitric oxide (NO) is a potent mediator in biologicnprocesses such as neurotransmission, inflammatory response, andnvascular homeostasis. NOSTRIN binds the enzyme responsible for NOnproduction, endothelial NO synthase (ENOS; MIM 163729), andntriggers the translocation of ENOS from the plasma membrane tonvesicle-like subcellular structures, thereby attenuatingnENOS-dependent NO production.
应用类型
WB
免疫原
This NOSTRIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the Central region of human NOSTRIN.
