Histones are basic nuclear proteins that are responsiblenfor the nucleosome structure of the chromosomal fiber inneukaryotes. Nucleosomes consist of approximately 146 bp of DNAnwrapped around a histone octamer composed of pairs of each of thenfour core histones (H2A, H2B, H3, and H4). The chromatin fiber isnfurther compacted through the interaction of a linker histone, H1,nwith the DNA between the nucleosomes to form higher order chromatinnstructures. This gene is intronless and encodes a member of thenhistone H2A family. Transcripts from this gene contain anpalindromic termination element.
应用类型
WB
免疫原
This HIST2H2AB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST2H2AB.
