The protein encoded by this gene belongs to the SMAD, anfamily of proteins similar to the gene products of the Drosophilangene 'mothers against decapentaplegic' (Mad) and the C. elegansngene Sma. SMAD proteins are signal transducers and transcriptionalnmodulators that mediate multiple signaling pathways. This proteinnfunctions as a transcriptional modulator activated by transformingngrowth factor-beta and is thought to play a role in the regulationnof carcinogenesis.
应用类型
WB,IHC,ICC
免疫原
This SMAD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 amino acids from the Central region of human SMAD3.
