TGFBRAP1 plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2.
应用类型
WB,IHC
免疫原
This TGFBRAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-528 amino acids from the C-terminal region of human TGFBRAP1.
