The protein encoded by this gene contains a RING fingernmotif and is highly similar to the ring finger proteins RNF28/MURF1nand RNF29/MURF2. In vitro studies demonstrated that this protein,nRNF28, and RNF29 form heterodimers, which may be important for thenregulation of titin kinase and microtubule-dependent signalnpathways in striated muscles. Alternatively spliced transcriptnvariants encoding distinct isoforms have been reported. [providednby RefSeq].
应用类型
WB,IHC
免疫原
This TRIM54 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TRIM54.