Theta-globin mRNA is found in human fetal erythroid tissuenbut not in adult erythroid or other nonerythroid tissue. Thentheta-1 gene may be expressed very early in embryonic life, perhapsnsometime before 5 weeks. Theta-1 is a member of the humannalpha-globin gene cluster that involves five functional genes andntwo pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mun- pseudoalpha-2 -pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'.nResearch supports a transcriptionally active role for the gene andna functional role for the peptide in specific cells, possibly thosenof early erythroid tissue.
应用类型
WB,IHC
免疫原
This HBQ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-28 amino acids from the N-terminal region of human HBQ1.