Fucose is typically found as a terminal modification ofnbranched chain glycoconjugates, but it also exists in directnO-linkage to serine or threonine residues within cystine knotnmotifs in epidermal growth factor (EGF; MIM 131530)-like repeats ornthrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is annO-fucosyltransferase that use THBS type-1 repeats as substratesn(Luo et al., 2006 [PubMed 16464857]).
应用类型
WB,IHC
免疫原
This POFUT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of human POFUT2.