This gene encodes a member of the glycosyltransferasenO-Fuc family. This enzyme adds O-fucose through an O-glycosidicnlinkage to conserved serine or threonine residues in the epidermalngrowth factor-like repeats of a number of cell surface and secretednproteins. O-fucose glycans are involved in ligand-induced receptornsignaling. Alternative splicing of this gene results in twontranscript variants encoding different isoforms. [provided bynRefSeq].
应用类型
WB,IHC
免疫原
This POFUT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human POFUT1.
