This gene encodes a protein that is a member of thensyntaxin or t-SNARE (target-SNAP receptor) family. These proteinsnare found on cell membranes and serve as the targets for V-SNARESn(vesicle-SNAP receptors) permitting specific synaptic vesiclendocking and fusion. A microdeletion in the region of chromosome 20nwhere this gene is located has been associated withnpseudohypoparathyroidism type Ib. Multiple transcript variantsnencoding different isoforms have been found for this gene.
应用类型
WB,FCM
免疫原
This STX16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-274 amino acids from the C-terminal region of human STX16.