This gene encodes a member of the RING-B-box-coiled-coiln(RBCC) family and encodes a protein with an N-terminal RING fingernmotif, a PRY domain and a C-terminal SPRY domain. The mousenortholog of this gene is specifically expressed in germ cells atnthe round spermatid stages during spermatogenesis and, whennoverexpressed, induces apoptosis. Alternatively spliced transcriptnvariants encoding distinct isoforms have been described. It may play a role in apoptosis (By similarity).
应用类型
WB,IHC
免疫原
This TRIM69 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-129 amino acids from the N-terminal region of human TRIM69.