The protein encoded by this gene is proteolyticallynprocessed to release a secreted peptide termed endothelin 1. Thisnpeptide is a potent vasoconstrictor and is produced by vascularnendothelial cells. Endothelin 1 also can affect the central nervousnsystem. Two transcript variants encoding different isoforms havenbeen found for this gene.
应用类型
WB,IHC,ICC
免疫原
This EDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-203 amino acids from the C-terminal region of human EDN1.
