This gene encodes a G-protein coupled receptor that bindsnneuropeptides of the corticotropin releasing hormone family thatnare major regulators of the hypothalamic-pituitary-adrenal pathway.nThe encoded protein is essential for the activation of signalntransduction pathways that regulate diverse physiological processesnincluding stress, reproduction, immune response and obesity.nAlternative splicing results in multiple transcript variants.
应用类型
WB,FCM
免疫原
This CRFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-119 amino acids from human CRFR1.
