This gene belongs to the subfamily of ubiquitouslynexpressed heterogeneous nuclear ribonucleoproteins (hnRNPs). ThenhnRNPs are RNA binding proteins and they complex with heterogeneousnnuclear RNA (hnRNA). These proteins are associated with pre-mRNAsnin the nucleus and appear to influence pre-mRNA processing andnother aspects of mRNA metabolism and transport. While all of thenhnRNPs are present in the nucleus, some seem to shuttle between thennucleus and the cytoplasm. The hnRNP proteins have distinct nucleicnacid binding properties. The protein encoded by this gene can actnas a tetramer and is involved in the assembly of 40S hnRNPnparticles. Multiple transcript variants encoding at least twondifferent isoforms have been described for this gene. [provided bynRefSeq].
应用类型
WB,IHC
免疫原
This HNRNPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-306 amino acids from the C-terminal region of human HNRNPC.
