The protein encoded by this gene is a member of thentransmembrane 4 superfamily, also known as the tetraspanin family.nMost of these members are cell-surface proteins that arencharacterized by the presence of four hydrophobic domains. Thenproteins mediate signal transduction events that play a role in thenregulation of cell development, activation, growth and motility.nThis encoded protein is a cell surface glycoprotein that is knownnto complex with integrins and other transmembrane 4 superfamilynproteins. It may play a role in T-cell-B-cell interactions.nAlternate splicing results in multiple transcript variants encodingndifferent isoforms.
应用类型
WB,FCM
免疫原
This CD37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the Central region of human CD37.
