The 3',5'-cyclic nucleotides cAMP and cGMP function asnsecond messengers in a wide variety of signal transductionnpathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs)ncatalyze the hydrolysis of cAMP and cGMP to the correspondingn5'-monophosphates and provide a mechanism to downregulate cAMP andncGMP signaling. This gene encodes a cAMP-specificnphosphodiesterase, a member of the cyclic nucleotidenphosphodiesterase family.
应用类型
WB
免疫原
This PDE7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 421-450 amino acids from the C-terminal region of human PDE7B.
